Reviews of "Monkeypox Outbreak in the Netherlands in 2022: Public Health Response, Epidemiological and Clinical Characteristics of the First 1000 Cases and Protection of the First-Generation Smallpox Vaccine"

Sharifa Nasreen

doi:doi:10.1162/2e3983f5.92e62af3

Reviews of "Monkeypox Outbreak in the Netherlands in 2022: Public Health Response, Epidemiological and Clinical Characteristics of the First 1000 Cases and Protection of the First-Generation Smallpox Vaccine"

Reviewer: S. Nasreen (University of Toronto) | 📗📗📗📗◻️

by Sharifa Nasreen

Published onDec 29, 2022

This Pub is a Review of

Monkeypox outbreak in the Netherlands in 2022: public health response, epidemiological and clinical characteristics of the first 1000 cases and protection of the first-generation smallpox vaccine

by Catharina E. van Ewijk, Fuminari Miura, Gini van Rijckevorsel, Henry J.C. de Vries, Matthijs R.A. Welkers, Oda E. van den Berg, Ingrid H.M. Friesema, Patrick van den Berg, Thomas Dalhuisen, Jacco Wallinga, Diederik Brandwagt, Brigitte A.G.L. van Cleef, Harry Vennema, Bettie Voordouw, Marion Koopmans, Annemiek A. van der Eijk, Corien M. Swaan, Margreet J.M. te Wierik, Tjalling Leenstra, Eline Op de Coul, Eelco Franz, and undefined undefined

Show Description
dx.doi.org

Description

AbstractIn early May 2022 a global outbreak of monkeypox (MPX) started among persons without a travel history to regions known to be enzootic for monkeypox-virus. On August 8 2022, the Netherlands reported its 1000thmonkeypox case representing a cumulative incidence of 55 per million population, one of the highest cumulative incidences worldwide. Here we describe the epidemiological characteristics and clinical presentation of the first 1000 monkeypox cases in the Netherlands, within the context of the public health response. Additionally, we explored risk factors for and estimated the protective effect of first-generation smallpox vaccine against more severe MPX.The first 1000 MPX cases, reported between May 20 and August 8 2022, were predominantly MSM aged 31-45 years. The vast majority of infections were acquired through sexual contact with casual partners in private or recreational settings including LGBTQIA+ venues in the Netherlands. This indicates that, although some larger upsurges occurred from point-source and/or travel related events, the outbreak is mainly characterised by sustained transmission within the Netherlands. More severe MPX was associated with having one or more comorbidities as well as having participated in more (3+) different sexual activities 21 days before symptom onset. We found a vaccine effectiveness of the prior first-generation smallpox vaccine against more severe MPX of 58% (95% CI 17-78%), suggesting moderate protection against more severe MPX symptoms on top of any possible protection by this vaccine against MPXV infection and disease.

To read the original manuscript, click the link above.

Reviewer 1 (Sharifa N…) | 📗📗📗📗◻️

RR:C19 Strength of Evidence Scale Key

📕 ◻️◻️◻️◻️ = Misleading

📙📙 ◻️◻️◻️ = Not Informative

📒📒📒 ◻️◻️ = Potentially Informative

📗📗📗📗◻️ = Reliable

📘📘📘📘📘 = Strong

To read the reviews, click the links below.

Connections

1 of 1

A Supplement to this Pub

Review 1: "Monkeypox Outbreak in the Netherlands in 2022: Public Health Response, Epidemiological and Clinical Characteristics of the First 1000 Cases and Protection of the First-Generation Smallpox Vaccine"

by Sharifa Nasreen

Published on Dec 29, 2022
rrid.mitpress.mit.edu

License

Creative Commons Attribution 4.0 International License (CC-BY 4.0)

Comments

Will Taylor:

I found your writing to be both informative and enjoyable. Keep up the great work!

Thank you

The Prestige City Hyderabad

Birla Courtyard:

Birla Courtyard is a testament to the harmonious coexistence of modern living and environmental consciousness

Sobha Neopolis:

Sobha Neopolis is now going to launch as soon as.

Prestige Park Ridge:

Prestige Park Ridge was thanked for this posting.

Purva Tranquility:

Purva Tranquility is a residential project located at S Medahalli near Sarjapur Road in Bangalore East

Century Trails:

Century Trails is solar powered and uses abundant amounts of sunlight to generate clean energy for public spaces and amenities

Purva Tranquility:

At Purva Tranquility, indulge in the height of luxury and peace.

Andrew Harry:

Thanks for taking the time to post such valuable information. Andrew

prestige park grove:

Prestige Park Grove Location Map

Prestige Park Grove A New Project By Prestige Group; Location:Whitefield, East, Bangalore.Route Details,Get Driving direction to Reach Prestige Park Grove

Birla Trimaya:

Birla Trimaya is a brand new massive mixed-use Township project in Shettigere just off Bangalore Airport

https://btrimaya.amebaownd.com/posts/47675910

provident ecopolitan:

Provident Ecopolitan

Sobha Neopolis:

Sobha Neopolis excellent Panathur Road location guarantees seamless access to all of Bangalore's major hubs. Both businesspeople and families will find this prime location to be ideal because it offers quick access to IT parks, shopping malls, hospitals, and schools. Sobha Neopolis is a sought-after location for those looking for the pinnacle of luxury living in Bangalore's bustling surroundings because of Sobha Limited's dedication to excellence.

Prestige Kings County:

Prestige Kings County is more than just a piece of ground it is a blank canvas on which imagination can take flight. The lines drawn there are not just boundaries but also the contours of a special journey known as home.

Prestige Serenity Shores Plan:

Prestige Serenity Shores redefines luxury by blending opulence, comfort, and convenience seamlessly. It's not just a residence; it's a symphony of sophistication that resonates with your discerning taste. Welcome to Prestige Serenity Shores, where luxury is not just an experience—it's a way of life, redefined to elevate your every moment.

Prestige Park Ridge Plan:

Prestige Park Ridge, located in the heart of Bangalore, offers a remarkable array of indoor games that cater to both leisurely relaxation and spirited competition. Step into a haven of entertainment and camaraderie where residents can engage in a variety of games, from classic favorites to modern challenges, all within the comfort of the project's luxurious confines.

Prestige Park Grove:

Prestige Park Grove Location provides easy access to educational institutions, healthcare services, shopping locations, and more, making daily life quite comfortable for its occupants.

Provident Ecopolitan:

Provident Ecopolitan is more than just a place to live, it is a symbol of refinement and grandeur that elevates everyday life to an amazing experience.

Prestige Southern Star:

Prestige Southern Star delivers an extraordinary living experience that raises the bar for modern urban living.

Prestige Park Grove:

Prestige Park Grove is more than just a residential complex; it is a harmonious blend of opulence and nature, designed to cater to every facet of a luxurious and comfortable lifestyle

Birla Trimaya Plan:

Birla Trimaya's pet-friendly properties foster a sense of community among pet lovers. Residents share a common bond – a love for animals – which often leads to lasting friendships and shared experiences. Walking paths, pet parks, and communal pet-friendly events provide opportunities for both pets and their owners to socialize and connect.

Provident Ecopolitan:

The advantage of both peace and connectivity is provided to residents of Provident Ecopolitan thanks to its excellent location. These opulent homes offer a tranquil retreat where residents can relax in the presence of nature because they are located outside of the city's busy life.

Provident Deansgate:

Bangalore's opulent living has never been more luxurious thanks to Provident Deansgate Luxury Apartments. This housing development epitomizes affluent living with its premier location, elegant design, first-rate amenities, and dedication to sustainability.

Prestige Lavender Fields Plan:

Prestige Lavender Fields presents an attractive opportunity for generating rental income. Its strategic location, modern amenities, quality design, and strong demand from tenants position it as a smart investment choice. By investing in this prestigious project, investors can benefit from both a luxurious living experience and a promising source of rental revenue in the heart of Bangalore.

jame lipz:

After the Covid-19 epidemic was stabilized, smallpox broke out again. Humans face new challenges and need to fleeing the complex again. We need to have accurate assessment and recognition of the epidemic situation to be able to come up with timely solutions.

otis jame:

Acquire a useful new knowledge. nyt wordle Thanks to the site for providing very good documentation and information.

Bryce Wo:

The RDF shredder separates waste into two parts: combustible and non-combustible.

The first step is pre-treatment, which breaks down the waste into smaller pieces and removes non-combustible material. This can include bag breaking, primary magnetic separation, or other methods.