Reviews of "Safety and Immunogenicity of a Bivalent Paratyphoid A-Typhoid Conjugate Vaccine in Healthy Indian Adults: A Phase I, Randomized, Active Controlled Study"

Megan Carey; Kathleen Neuzil; Matthew Laurens

doi:doi:10.1162/2e3983f5.41c620fb

Reviews of "Safety and Immunogenicity of a Bivalent Paratyphoid A-Typhoid Conjugate Vaccine in Healthy Indian Adults: A Phase I, Randomized, Active Controlled Study"

Reviewers: M Carey (London School of Hygiene and Tropical Medicine) | 📗📗📗📗◻️ • K Neuzil (University of Maryland) | 📗📗📗📗◻️ • M Laurens (University of Maryland) | 📘📘📘📘📘

by Megan Carey, Kathleen Neuzil, and Matthew Laurens

Published onFeb 14, 2024

This Pub is a Review of

Safety and Immunogenicity of a Bivalent Paratyphoid A-Typhoid Conjugate Vaccine in Healthy Indian Adults: A Phase I, Randomized, Active Controlled Study

by Kulkarni, Prasad S., Potey, Anirudha Vyankatesh, Bharati, Sandesh, Kunhihitlu, Anil, Narasimha, Bharath, Sindhu, Y, Dharmadhikari, Abhijeet, Gavade, Vinay, Kamat, Chandrashekhar D., Mallya, Asha Dinesh, Sarma, Annamraju D., Goel, Sunil, Pisal, Sambhaji S., Poonawalla, Cyrus, Venkatesan, Rajaram, Jones, Elizabeth, Flaxman, Amy, Kim, Young Chan, Pollard, Andrew J., and Group, TCV-01 Study

Show Description
papers.ssrn.com

Description

Background: Enteric fever caused by Salmonella Typhi and Paratyphi A is an important public health problem, especially in low- and middle-income countries with

To read the original manuscript, click the link above.

Summary of Reviews: This preprint details the result of a phase 1 vaccine trial of a bivalent Paratyphoid A-Typhoid Conjugate Vaccine in healthy adults. The authors found that this vaccine was safe and immunogenic for both typhoid and paratyphoid antigen. The general consensus among reviewers was that this study was reliable, highlights important evidence for the immunogenicity for this novel vaccine, and has important implications for future clinical development.

Reviewer 1 (Megan C…) | 📗📗📗📗◻️

Reviewer 2 (Kathleen N…) | 📗📗📗📗◻️

Reviewer 3 (Matthew L…) | 📘📘📘📘📘

RR:C19 Strength of Evidence Scale Key

📕 ◻️◻️◻️◻️ = Misleading

📙📙 ◻️◻️◻️ = Not Informative

📒📒📒 ◻️◻️ = Potentially Informative

📗📗📗📗◻️ = Reliable

📘📘📘📘📘 = Strong

To read the reviews, click the links below.

Connections

1 of 3

A Supplement to this Pub

Review 1: "Safety and Immunogenicity of a Bivalent Paratyphoid A-Typhoid Conjugate Vaccine in Healthy Indian Adults: A Phase I, Randomized, Active Controlled Study"

by Megan Carey

Show Description
Published on Feb 14, 2024
rrid.mitpress.mit.edu

Description

The general consensus among reviewers was that this study was reliable, highlights important evidence for the immunogenicity for this novel vaccine, and has important implications for future clinical development.

A Supplement to this Pub

Review 2: "Safety and Immunogenicity of a Bivalent Paratyphoid A-Typhoid Conjugate Vaccine in Healthy Indian Adults: A Phase I, Randomized, Active Controlled Study"

by Kathleen Neuzil

Show Description
Published on Feb 14, 2024
rrid.mitpress.mit.edu

Description

A Review of this Pub

Review 3: "Safety and Immunogenicity of a Bivalent Paratyphoid A-Typhoid Conjugate Vaccine in Healthy Indian Adults: A Phase I, Randomized, Active Controlled Study"

by Matthew Laurens

Show Description
Published on Feb 14, 2024
rrid.mitpress.mit.edu

Description

License

Creative Commons Attribution 4.0 International License (CC-BY 4.0)

Comments

Bande mr:

Ang swerte mo’y magsisimula sa 99bet - https://99bet-8.com! Mag-sign up bilang bagong miyembro at awtomatikong makakuha ng $100 bonus. Punan lamang ang simpleng form ng registration at i-enjoy ang mga premium na laro online.

Bande mr:

Magparehistro ngayon sa inplay - https://inplay-8.com at tanggapin ang iyong $100 welcome bonus! Napakadaling sumali, at siguradong panalo ka na agad mula sa simula. Subukan ang slots, live casino, at sports betting na may dagdag na pondo para sa mas malaking pagkakataong manalo.

sgfddfyhjyh [email protected]:

A data breach or cyber attack can severely damage a company's reputation and erode customer trust security for your web applications. Implementing robust cyber security measures helps in protecting the brand's reputation and maintaining a positive public image.

sgfddfyhjyh [email protected]:

Chicken livers are rich in high-quality protein, which is essential for muscle growth and repair nandos chicken livers.