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Reviews of "SARS-CoV-2 spike downregulates tetherin to enhance viral spread"

Reviewers: Chin-Tien Wang | ๐Ÿ“—๐Ÿ“—๐Ÿ“—๐Ÿ“—โ—ป๏ธ โ€ข Barry Milavetz (University of North Dakota) | ๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜

Published onAug 13, 2021
Reviews of "SARS-CoV-2 spike downregulates tetherin to enhance viral spread"

To read the original manuscript, click the link above.

Summary of Reviews: This preprint demonstrates that host cells employ a known pathway in which interferon-induced tetherin โ€œtethersโ€ SARS-CoV-2 to the inner plasma membrane to restrict viral exit. Reviewers recognize the data as reliable with minor revisions needed.

Reviewer 1 (Chin-Tien Wang) | ๐Ÿ“—๐Ÿ“—๐Ÿ“—๐Ÿ“—โ—ป๏ธ

Reviewer 2 (Barry Milavetz) | ๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜

RR:C19 Strength of Evidence Scale Key

๐Ÿ“• โ—ป๏ธโ—ป๏ธโ—ป๏ธโ—ป๏ธ = Misleading

๐Ÿ“™๐Ÿ“™ โ—ป๏ธโ—ป๏ธโ—ป๏ธ = Not Informative

๐Ÿ“’๐Ÿ“’๐Ÿ“’ โ—ป๏ธโ—ป๏ธ = Potentially Informative

๐Ÿ“—๐Ÿ“—๐Ÿ“—๐Ÿ“—โ—ป๏ธ = Reliable

๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜๐Ÿ“˜ = Strong

To read the reviews, click the links below.ย 


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