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Reviews of "United States Influenza 2022-2023 Season Characteristics as Inferred from Wastewater Solids, Influenza Hospitalization and Syndromic Data"

Reviewers: A Gitter (UTHealth Houston) | 📘📘📘📘📘 • C Oh (University of Florida) | 📘📘📘📘📘

Published onOct 23, 2023
Reviews of "United States Influenza 2022-2023 Season Characteristics as Inferred from Wastewater Solids, Influenza Hospitalization and Syndromic Data"
key-enterThis Pub is a Review of
United States influenza 2022-2023 season characteristics as inferred from wastewater solids, influenza hospitalization and syndromic data
United States influenza 2022-2023 season characteristics as inferred from wastewater solids, influenza hospitalization and syndromic data
Description

Abstract Influenza A virus (IAV) causes significant morbidity and mortality in the United States and has pandemic potential. Identifying IAV epidemic patterns is essential to inform the timing of vaccines and non-pharmaceutical interventions. In a prospective, longitudinal study design, we measured IAV RNA in wastewater settled solids at 163 wastewater treatment plants across 33 states to characterize the 2022-2023 influenza season at the state, health and human services (HHS) regional, and national scales. Influenza season onset, offset, duration, peak, and intensity using IAV RNA in wastewater were compared with those determined using laboratory-confirmed influenza hospitalization rates and outpatient visits for influenza-like illness (ILI). The onset for HHS regions as determined by IAV RNA in wastewater roughly corresponded with those determined using ILI when the annual geometric mean of IAV RNA concentration was used as baseline (i.e., the threshold that triggers onset), although offsets between the two differed. IAV RNA in wastewater provided early warning of onset, compared to the ILI estimate, when the baseline was set at twice the limit of IAV RNA detection in wastewater. Peak when determined by IAV RNA in wastewater generally preceded peak determined by IAV hospitalization rate by two weeks or less. Wastewater settled solids data is an IAV-specific indicator that can be used to augment clinical surveillance for seasonal influenza epidemic timing and intensity.

To read the original manuscript, click the link above.

Summary of Reviews: This preprint explores the use of wastewater monitoring to augment traditional surveillance methods for seasonal influenza trends, looking at the 2022-2023 influenza season in particular. Reviewers agreed that this is a strong preprint with important public health implications and well-detailed, appropriate methods.

Reviewer 1 (Anna G…) | 📘📘📘📘📘

Reviewer 2 (Chamteut O…) | 📘📘📘📘📘

RR:C19 Strength of Evidence Scale Key

📕 ◻️◻️◻️◻️ = Misleading

📙📙 ◻️◻️◻️ = Not Informative

📒📒📒 ◻️◻️ = Potentially Informative

📗📗📗📗◻️ = Reliable

📘📘📘📘📘 = Strong

To read the reviews, click the links below. 

Comments
2
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shrktzamzam shrktzamzam:

شركة زمزم لمكافحة النمل الأبيض في جازان هي شركة متخصصة ومعترف بها في مجال مكافحة النمل الأبيض والآفات الحشرية في المنطقة. توفر هذه الشركة خدمات مكافحة فعالة للنمل الأبيض، الذي يعتبر تهديدًا كبيرًا للمنازل والممتلكات في جميع أنحاء جازان.تعتمد شركة زمزم على فريق من الخبراء والمتخصصين في مجال مكافحة النمل الأبيض، وتستخدم أحدث التقنيات والمواد الآمنة للبيئة للقضاء على هذه الآفة ومنع عودتها. تهدف الشركة إلى حماية الممتلكات والمنازل والمباني من التلف الناجم عن النمل الأبيض وضمان بيئة صحية وآمنة للعملاء.بفضل خدمات شركة زمزم لمكافحة النمل الأبيض، يمكن لسكان جازان الاستمتاع بممتلكاتهم دون القلق بشأن هذه الآفة الضارة. تعتبر هذه الشركة خيارًا موثوقًا للأفراد والمنشآت الباحثين عن حلول فعالة لمكافحة النمل الأبيض في المنطقة.

شركة علاج النمل الابيض بجازان




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Thank you! Winter will have many viruses that affect human health drift boss