Reviewers: G Zeng (Sun Yat-sen University) | ๐๐๐๐โป๏ธ โข L Vitetta (The University of Sydney) | ๐๐๐๐โป๏ธ
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Summary of Reviews: This preprint finds that: 1) gut microbiota of post-COVID subjects had predominance of antibiotic-resistance Enterobacteriaceae strains compared to healthy controls; and 2) fecal transplant from COVID-19 patients into germ free mice resulted in worse outcomes in mice with pulmonary infection by multidrug-resistant Klebsiella pneumoniae. The reviewers found this study to be reliable and that its findings suggest interventions targeting gut microbiota may be a potential treatment for sequelae after COVID-19.
Reviewer 1 (Gucheng Zโฆ) | ๐๐๐๐โป๏ธ
Reviewer 2 (Luis Vโฆ) | ๐๐๐๐โป๏ธ
RR:C19 Strength of Evidence Scale Key ๐ โป๏ธโป๏ธโป๏ธโป๏ธ = Misleading ๐๐ โป๏ธโป๏ธโป๏ธ = Not Informative ๐๐๐ โป๏ธโป๏ธ = Potentially Informative ๐๐๐๐โป๏ธ = Reliable ๐๐๐๐๐ = Strong |
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Creative Commons Attribution 4.0 International License (CC-BY 4.0)
