Reviewers: G Zeng (Sun Yat-sen University) | ππππβ»οΈ β’ L Vitetta (The University of Sydney) | ππππβ»οΈ
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Summary of Reviews: This preprint finds that: 1) gut microbiota of post-COVID subjects had predominance of antibiotic-resistance Enterobacteriaceae strains compared to healthy controls; and 2) fecal transplant from COVID-19 patients into germ free mice resulted in worse outcomes in mice with pulmonary infection by multidrug-resistant Klebsiella pneumoniae. The reviewers found this study to be reliable and that its findings suggest interventions targeting gut microbiota may be a potential treatment for sequelae after COVID-19.
Reviewer 1 (Gucheng Zβ¦) | ππππβ»οΈ
Reviewer 2 (Luis Vβ¦) | ππππβ»οΈ
RR:C19 Strength of Evidence Scale Key π β»οΈβ»οΈβ»οΈβ»οΈ = Misleading ππ β»οΈβ»οΈβ»οΈ = Not Informative πππ β»οΈβ»οΈ = Potentially Informative ππππβ»οΈ = Reliable πππππ = Strong |
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