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Reviews of "Serum Sphingosine-1-Phosphate as Novel Prognostic and Predictive Biomarker for COVID-19 Severity and Morbidity and Its Implications in Clinical Management"

Reviewers: Yoh Takuwa (Kanazawa University) | πŸ“’πŸ“’πŸ“’β—»οΈβ—»οΈ β€’ Hideru Obinata (Gunma University) | πŸ“’πŸ“’πŸ“’β—»οΈβ—»οΈ β€’ Markus GrΓ€ler (Jena University Hospital) | πŸ“™πŸ“™β—»οΈβ—»οΈβ—»οΈ β€’ Georgios Grammatikos (Goethe University Frankfurt) | πŸ“’πŸ“’πŸ“’β—»οΈβ—»οΈ

Published onSep 22, 2020
Reviews of "Serum Sphingosine-1-Phosphate as Novel Prognostic and Predictive Biomarker for COVID-19 Severity and Morbidity and Its Implications in Clinical Management"

To read the original manuscript, click the link above.

Summary of Reviews: This potentially informative article with some methodological flaws suggests that serum Sphingosine-1-Phosphate (S1P) is associated with COVID-19 severity. Further research is needed to understand if serum S1P could be provided therapeutically to reduce COVID-19 severity.

Reviewer 1 (Yoh Takuwa) | πŸ“’πŸ“’πŸ“’β—»οΈβ—»οΈ

Reviewer 2 (Hideru Obinata) | πŸ“’πŸ“’πŸ“’ ◻️◻️

Reviewer 3 (Markus GrΓ€ler) | πŸ“™πŸ“™ ◻️◻️◻️

Reviewer 4 (Georgios Grammatikos) | πŸ“’πŸ“’πŸ“’ ◻️◻️

RR:C19 Strength of Evidence Scale Key

πŸ“• ◻️◻️◻️◻️ = Misleading

πŸ“™πŸ“™ ◻️◻️◻️ = Not Informative

πŸ“’πŸ“’πŸ“’ ◻️◻️ = Potentially Informative

πŸ“—πŸ“—πŸ“—πŸ“—β—»οΈ = Reliable

πŸ“˜πŸ“˜πŸ“˜πŸ“˜πŸ“˜ = Strong

To read the reviews, click the links below.

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