Description
Background:Β Since December 2019, COVID-19 has widely spread throughout the world, causing thousands of deaths. Clinical characteristics of COVID-19 patie
Reviewers: Yoh Takuwa (Kanazawa University) | πππβ»οΈβ»οΈ β’ Hideru Obinata (Gunma University) | πππβ»οΈβ»οΈ β’ Markus GrΓ€ler (Jena University Hospital) | ππβ»οΈβ»οΈβ»οΈ β’ Georgios Grammatikos (Goethe University Frankfurt) | πππβ»οΈβ»οΈ
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Summary of Reviews: This potentially informative article with some methodological flaws suggests that serum Sphingosine-1-Phosphate (S1P) is associated with COVID-19 severity. Further research is needed to understand if serum S1P could be provided therapeutically to reduce COVID-19 severity.
Reviewer 1 (Yoh Takuwa) | πππβ»οΈβ»οΈ
Reviewer 2 (Hideru Obinata) | πππ β»οΈβ»οΈ
Reviewer 3 (Markus GrΓ€ler) | ππ β»οΈβ»οΈβ»οΈ
Reviewer 4 (Georgios Grammatikos) | πππ β»οΈβ»οΈ
RR:C19 Strength of Evidence Scale Key π β»οΈβ»οΈβ»οΈβ»οΈ = Misleading ππ β»οΈβ»οΈβ»οΈ = Not Informative πππ β»οΈβ»οΈ = Potentially Informative ππππβ»οΈ = Reliable πππππ = Strong |
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