Reviews of "Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses"

Seema Mishra; Nicolas Winssinger; Lluc Farrera-Soler; Jean-Pierre Daguer; Sofia Barluenga

doi:doi:10.1162/2e3983f5.3b8385ea

Reviews of "Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses"

Reviewers: Seema Mishra (University of Hyderabad) | 📗📗📗📗 ◻️ • Nicolas Winssinger, Lluc Farrera-Soler, Jean-Pierre Daguer, Sofia Barluenga (University of Geneva) | 📗📗📗📗 ◻️

by Seema Mishra, Nicolas Winssinger, Lluc Farrera-Soler, Jean-Pierre Daguer, and Sofia Barluenga

Published onSep 02, 2020

This Pub is a Review of

Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses

by Nischay Mishra, Xi Huang, Shreyas Joshi, Cheng Guo, James Ng, Riddhi Thakkar, Yongjian Wu, Xin Dong, Qianlin Li, Richard Pinapati, Eric Sullivan, Adrian Caciula, Rafal Tokarz, Thomas Briese, Jiahai Lu, and W. Ian Lipkin

Show Description
Published on Aug 14, 2020
www.biorxiv.org

Description

Serodiagnosis of SARS-CoV-2 infection is impeded by immunological cross-reactivity to the human coronaviruses (HCoV) SARS-CoV-2, SARS-CoV-1, MERS-CoV, OC43, 229E, HKU1, and NL63. Here we report the identification of humoral immune responses to SARS-CoV-2 and other HCoV peptides that can be used to detect asymptomatic, mild and, severe SARS-CoV-2 infections, and may enable the discovery of biomarkers for immunity following infection or vaccination.

To read the original manuscript, click the link above.

Summary of Reviews: This study presents a microarray-based screen that identifies immunoreactive peptide fragments recognized by antibodies present in COVID19+ patients. The primary findings are reliable; however, extrapolating these findings to other analytical approaches require validation.

Reviewer 1 (Seema Mishra) | 📗📗📗📗◻️

Reviewer 2 (Nicolas Winssinger, Lluc Farrera-Soler, Jean-Pierre Daguer, Sofia Barluenga) | 📗📗📗📗 ◻️

RR:C19 Strength of Evidence Scale Key

📕 ◻️◻️◻️◻️ = Misleading

📙📙 ◻️◻️◻️ = Not Informative

📒📒📒 ◻️◻️ = Potentially Informative

📗📗📗📗◻️ = Reliable

📘📘📘📘📘 = Strong

To read the reviews, click the links below.

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A Supplement to this Pub

Review 2: "Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses"

by Nicolas Winssinger, Lluc Farrera-Soler, Jean-Pierre Daguer, and Sofia Barluenga

Show Description
Published on Sep 02, 2020
rrid.mitpress.mit.edu

Description

This study presents a microarray-based screen that identifies immunoreactive peptide fragments recognized by antibodies present in COVID19+ patients. The primary findings are reliable; however, extrapolating these findings to other analytical approaches require validation.

A Supplement to this Pub