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Reviews of "Clinical validation of innovative, low cost, kit-free, RNA processing protocol for RT-PCR based COVID-19 testing."

Reviewers: Aditi Bhargava Bhargava (UCSF) | 📒📒📒◻️◻️ • Mohamed Sharafeldin (University of Oxford) | 📙📙◻️◻️◻️

Published onAug 20, 2020
Reviews of "Clinical validation of innovative, low cost, kit-free, RNA processing protocol for RT-PCR based COVID-19 testing."

To read the original manuscript, click the link above.

Summary of Reviews: While informative, there are many flaws in the protocol testing if SARS-CoV2 RNA can be amplified from nasopharyngeal swab samples. The protocol does not appear to support claims that authors have made that this approach will decrease assay time, reduce cost, and instrumentation.

Reviewer 1 (Aditi Bhargava Bhargava) | 📒📒📒 ◻️◻️

Reviewer 2 (Mohamed Sharafeldin) | 📙📙 ◻️◻️◻️

RR:C19 Strength of Evidence Scale Key

📕 ◻️◻️◻️◻️ = Misleading

📙📙 ◻️◻️◻️ = Not Informative

📒📒📒 ◻️◻️ = Potentially Informative

📗📗📗📗◻️ = Reliable

📘📘📘📘📘 = Strong

To read the reviews, click the links below.

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